Big Bad Mouse

Big Bad Mouse

Big Bad Mouse is a British stage play and theatrical comedic farce by Phillip King and Falkland L. Carey. Although not specifically written for Jimmy Edwards and Eric Sykes, it became a vehicle for the British comedy actors and has been revived many times with other stars right up to 2008. Basd on an original idea by Ivan Butler, Big Bad Mouse was first staged in 1964 but did not become a box office hit until Edwards and Sykes took over the lead roles and toured the show across the UK in 1966 and 1967. It was also a top attraction in London's West End for three years between 1967 and 1970. The anarchic pair brought their own talents to play and twisted the plot and dialogue out of all recognition. No two shows were identical and it became an increasingly fluid experience, including audience participation and regular breaking of the 'fourth wall' between the stage and the audience. The role of the supporting cast quickly became one of trying to keep straight faces while steering the show on track and somewhere close to the original script, while the show's two stars generally played the fool.

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Canyon mouse

The canyon mouse (Peromyscus crinitus) is a gray-brown mouse found in many states of the western United States and northern Mexico. Its preferred habitat is arid, rocky desert. It is the only species in the Peromyscus crinitus species group. Canyon mice eat seeds, green vegetation, and insects. They breed in the spring and summer. Females can produce multiple litters of between two and five young every year. Canyon mice are nocturnal and are active through the year. They usually nest among or below rocks in burrows.

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False canyon mouse

The false canyon mouse or Coronados deer mouse, (Peromyscus pseudocrinitus) is a species of rodent in the family Cricetidae. It is known only from Coronados Island, a small island in the Gulf of California, part of Baja California Sur, Mexico. The species is threatened by predation by feral cats, and the IUCN has assessed its conservation status as "critically endangered".

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why isnt the mouse for my computer not working?

did you try unpluging the mouse and plugging it back in or rebooting your computere

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Effects in ALS in a mouse model

Researchers discovered that a mouse model of Amyotrophic lateral sclerosis suffers from an abnormal gut microbiome, and that supplementing these mice with Akkermansia muciniphila improved their symptoms, slowed the progression of their disease, and increased their survival. Moreover, they found that A. muciniphila produce the vitamin nicotinamide, which when injected into the diseased mice improved their motor symptoms, although it did not increase their lifespan as the bacteria had. They also found lower levels of nicotinamide in the circulation and the cerebrospinal fluid (CSF) of a small sample human ALS patients compared to their family members, and lower levels of A. muciniphila in their stool. In addition, ALS patients with lower levels of nicotinamide in their blood tended to have worse symptoms than patients with higher levels.

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Claire's mouse lemur

Claire's mouse lemur (Microcebus mamiratra), or the Nosy Be mouse lemur, is a newly described species of lemur from the genus of the mouse lemurs (Microcebus). It lives on the island Nosy B in the Antsiranana province of Madagascar, and on the mainland near the village of Manehoka, including Lokobe Reserve. The scientific type name, mamiratra, comes from Malagasy and means "clear and bright"; this refers the Theodore F. and Claire M. Hubbard Family Foundation, which has contributed to genetic research on Madagascar. This species is closely related to another new species, "M. species nova # 5"; which is related to the Sambirano mouse lemur, Microcebus sambiranensis, and the northern rufous mouse lemur, Microcebus tavaratra. This lemur is, with a weight of 60 g, average for its genus. The fur of the upper part is reddish-brown and becomes darker in the middle of the back. The tail is also reddish-brown, but the underbelly is white or creamy. It has a total length of 26 to 28 centimeters, including 15 to 17 centimeters of tail. The species status of Claire's mouse lemur has been recently challenged by a broad study of nuclear DNA and gene trees in mouse lemurs. Results showed that although the mitochondrial DNA differed from that of the Sambirano mouse lemur, its nuclear DNA did not. This is likely due to female philopatry. Since females stay close to the home range in which they were born, mitochondrial DNA, which is inherited from the mother, is likely to remain similar within a small area while nuclear DNA within a species is likely to be similar over a much larger area. According to the study, this is the case for Claire's mouse lemur. For this reason, it was suggested that Claire's mouse lemur no longer be recognized as a distinct species.